Standard guitar tuning is the default method for tuning a six-string guitar, where the open strings are tuned to the notes E, A, D, G, B, and E from the lowest pitch to the highest. This specific arrangement is built on a series of perfect fourth intervals, with a major third between the G and B strings. This unique layout balances the physical comfort of your fretting hand and provides musical convenience for playing common chords and scales across the fretboard.